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| Registros recuperados: 2.072 | |
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| Kiffer,Carlos R.V.; Kuti,Joseph L.; Mendes,Caio M.F.; Oplustil,Carmen P.; Amarante,Jorge B.; Biancalana,Maria L.; Xavier,Nelson; Nicolau,David P.. |
| Pharmacodynamic analyses were proposed to determine optimal empirical antibiotic therapy against Gram-negative bacteria isolated in a Brazilian ICU. Due to high resistance rates, standard regimens of cefepime, ciprofloxacin, meropenem, and piperacillin/tazobactam were not able to attain significant bactericidal CFR. Prolonged infusion of meropenem achieved 88% CFR, making it a possible empirical regimen in this ICU until susceptibilities become available. Still, even through administration of high dose prolonged infusions, 12.0% of simulated subjects did not achieve bactericidal exposure, suggesting that combination therapy would frequently be required in this setting. In conclusion, we recommend that in the presence of identified resistance problems among... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pharmacodynamics; Resistance; Carbapenem; Meropenem. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000200001 |
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| Lanzieri,Tatiana M.; Cunha,Clóvis Arns da; Cunha,Rejane B.; Arguello,D. Fermin; Devadiga,Raghavendra; Sanchez,Nervo; Barria,Eduardo Ortega. |
| Abstract Objectives: To estimate acute otitis media incidence among young children and impact on quality of life of parents/caregivers in a southern Brazilian city. Methods: Prospective cohort study including children 0-5 years of age registered at a private pediatric practice. Acute otitis media episodes diagnosed by a pediatrician and impact on quality of life of parents/caregivers were assessed during a 12-month follow-up. Results: During September 2008-March 2010, of 1,136 children enrolled in the study, 1074 (95%) were followed: 55.0% were ≤2 years of age, 52.3% males, 94.7% white, and 69.2% had previously received pneumococcal vaccine in private clinics. Acute otitis media incidence per 1000 person-years was 95.7... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Acute otitis media; Children; Incidence; Quality of life. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000400468 |
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| Hasanain,Ahmad; Mahdy,Reem; Mohamed,Asmaa; Ali,Mostafa. |
| Abstract Aim The aim of this study was to compare both the efficacy and safety profile of the WHO-recommended, dual therapy (doxycycline–rifampin) to a quinolone-based, triple therapy (doxycycline–rifampin–levofloxacin) for treating acute/subacute brucellosis. Patients and methods We studied 107 consecutive, naïve patients with acute/subacute brucellosis admitted to Assiut University Hospital. Patients were randomly allocated to receive the dual therapy of doxycycline–rifampin (group-A) or to receive the triple therapy of doxycycline–rifampin–levofloxacin (group-B). Acute/subacute brucellosis was diagnosed based on the presence of: (1) contact with animals or fresh animal products, (2) suggestive clinical manifestations of less than one-year duration,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Brucellosis; Doxycycline; Rifampin; Levofloxacin. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000300005 |
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| Entonu,P.E.; Agwale,S.M.. |
| In order to amalgamate research findings on HIV/AIDS in Nigeria as well as the trend of the infection in a concise manner, we reviewed published articles on the HIV/AIDS situation in Nigeria. We categorized this review into several subheadings. The HIV prevalence rate has continued to rise steadily from less than 0.1% in 1987, to 5.8% in 2001, with a slight decrease in 2003 to 5.0%. Although the knowledge about HIV and its mode of transmission is widespread, it is however disheartening to note that this did not result into appreciable attitudinal change and behavior modification among Nigerians. Both HIV-1 and HIV-2 have been identified in Nigeria, with HIV-1 being the predominant type. Furthermore, several subtypes like subtypes A, B, C, G and J have been... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HIV; Review; Nigeria. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000600011 |
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| Mamishi,Setareh; Eghbali,Aiden Nasiri; Rezaei,Nima; Abolhassani,Hassan; Parvaneh,Nima; Aghamohammadi,Asghar. |
| Primary antibody deficiencies (PADs) are a heterogeneous group of disorders, characterized by hypogammaglobulinemia and increased susceptibility to bacterial infections, leading to hospitalizations. This study was performed to determine the main infectious causes of hospital admissions in selective Iranian patients with PADs. Forty patients with PADs, who were admitted to the Infectious Ward of Children's Medical Center Hospital during a 14-year period, were reviewed in this study. There were 115 documented episodes of hospital admission during a 14-year period. The average length of hospital stay was 33.30 ± 25.72 days. Pneumonia was the most prominent infection leading to hospitalization among these patients (n = 48), followed by gastroenteritis (n =... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Infection; Hospitalization; Primary antibody deficiencies. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000400007 |
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| Simões-Barbosa,Augusto; Feijó,Gilvânia Coutinho; Silva,Joaquim Xavier da; Leal,Isabel Irene Rama; Barbosa,Tânia Wanderley Paes. |
| The notification of sexually transmitted diseases (STD) is a prime component of well-designed public health policy. However, peculiar aspects of STD must be taken into account for the correct management of surveillance activities. Here, we describe the distribution of the most common sexually transmitted diseases among patients attended by the gynecological clinics of the principal public hospitals of Brasilia and the Federal District, Brazilian capital, during six years. A total of 142,158 patients had their cervicovaginal samples collected for Papanicolaou preparations and eventual biopsies. Diagnosis was made according to cytological and histological alterations, distinguishing among vaginal infections, and pre-cancerous and cancerous cervical lesions.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sexually transmitted diseases; STD notification; STD epidemiology. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000300002 |
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| Registros recuperados: 2.072 | |
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